Johannes C. Textor

A human-in-the-loop approach for faster cell tracking

This paper introduces a human-in-the-loop cell tracking framework that integrates human feedback during tracking to reduce correction needs and improve track quality.

Hiltonol and Protamine-RNA stimulation induce an immune-activating transcriptome profile in cDC1s

The paper evaluates how Hiltonol and protamine-RNA stimulate human cDC1s, showing similar transcriptome changes related to immune activation without synergistic effects.

Differential T cell receptor clonotype abundance analysis with similarity-based counts weighting

The paper introduces a pre-processing method for TCR-seq data using sequence similarity-based weighting to improve differential abundance analysis and reduce false positives.

Compartment size and proliferation shape the murine T cell receptor repertoire in splenic T- and B cell zones during an immune response

This study shows that compartment size and proliferation, rather than TCR sequence features, shape the TCR repertoire distribution in splenic T- and B cell zones during immune responses.

Systematic analysis of immune cell motility leveraging Immunemap, an open intravital microscopy atlas

The paper introduces Immunemap, an open intravital microscopy atlas, and uses unsupervised learning to identify four immune cell motility patterns, including previously uncharacterized behaviors.

Cooperative motility emerges in crowds of T cells and prevents jamming

This study shows T cells avoid jamming in crowds by synchronizing motion, unlike neutrophils, through adhesion and force transmission mechanisms.

CelltrackR: an R package for fast and flexible analysis of immune cell migration data

CelltrackR provides an R package for analyzing immune cell migration data with tools for data management, quality control, migration statistics, clustering, and simulation.

Artistoo: build, share, and explore simulations of cells and tissues in the web browser

Artistoo enables interactive Cellular Potts Model simulations in web browsers without requiring specialized software or expertise.