Author

Sudharsan Kannan

University of Wisconsin–MadisonORCID 0000-0002-0460-0068Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:electrophysiology· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

Gail A. RobertsoniD· 2 shared Liliana R. ErnandeziD· 2 shared Anjon AudhyaiD· 1 shared William KasbergiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersBiophysics

Gail A. RobertsonORCID

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2 papers

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedAug 18, 2026

An ER retention motif controls the heteromeric stoichiometry of hERG1a/1b channels

Sudharsan Kannan, Liliana R. Ernandez, Gail A. Robertson

This study identifies an ER retention motif in hERG1b that enforces a fixed 2:2 stoichiometry in hERG1a/1b channels, with disruption leading to random subunit composition.

DOI 10.1073/pnas.2605305123

humanelectrophysiology

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Cell BiologyProceedings of the National Academy of SciencesPeer-reviewedJul 1, 2025

A privileged ER compartment for post-translational heteromeric assembly of an ion channel

Sudharsan Kannan, William Kasberg, Liliana R. Ernandez…·Gail A. Robertson

The paper identifies a specialized ER compartment that sequesters hERG1b subunits, enabling post-translational heteromeric assembly with hERG1a instead of degradation.

3 citations

humanproteomics

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