William Kasberg

The paper shows macrophages remove protein aggregates from other cells via trogocytosis, driven by lysosomal stress and tmCSF1 signaling.

The paper develops mRNAbow, a system for generating low-toxicity mRNAs for multiplexed fluorescent imaging in diverse cellular and organismal systems.

The paper shows glucose starvation impairs ER-to-Golgi trafficking, reducing surface proteins like E-cadherin and promoting metastasis through AMPK and ULK1 signaling.

The paper identifies a specialized ER compartment that sequesters hERG1b subunits, enabling post-translational heteromeric assembly with hERG1a instead of degradation.

The paper defines cardiac nerve architecture during development, disease, and regeneration using 3D modeling and imaging, showing regenerating myocardium reestablishes physiological innervation.