Device encapsulated MSCs for adaptive secretome therapy to effectively target ischaemic heart injury
Andrew R. Kompa, David W. Greening, Jarmon G. Lees, Anne M. Kong, Jonathon Cross, Ashley Nowland, Ren J. Phang, Saba Naghipour, Yali Deng, Jack R. T. Darby, Lina Mariana, Cameron Kos, Tanya Hall, Andrew E. Newcomb, James J.H. Chong, , Shiang Yong Lim
This paper develops a device-encapsulated MSC system for sustained secretome delivery to treat ischaemic heart injury, showing improved cardiac function and reduced remodelling in rats.
Stem Cell Research & Therapy · Dec 5, 2025Peer-reviewedPathology