Anne M. Kong

The paper develops a human cardiac microtissue model to study ischemia-reperfusion injury and shows that nanovesicles improve cardiomyocyte survival and function through proteomic changes.

This study uses iPSCs from FRDA patients to model cardiac dysfunction, finding transcriptional dysregulation and phenotypes like increased cell size and mitochondrial stress.

This paper shows DRP1 inhibition reduces doxorubicin-induced cardiotoxicity while maintaining its anticancer effects in multiple cancer models.

This paper develops a device-encapsulated MSC system for sustained secretome delivery to treat ischaemic heart injury, showing improved cardiac function and reduced remodelling in rats.

The paper uses long-read sequencing to map Drp1 transcript variants in human and mouse tissues, revealing tissue-specific expression and isoform-dependent mitochondrial fission activity.