MARCO C. ONOFRJ

Long-term dynamic changes of NMDA receptors following an excitotoxic challenge

The paper investigates how NMDA receptors in nNOS (+) neurons change over time after excitotoxic stress, revealing redox-driven adaptations that reduce neuronal vulnerability.

Inhibition of de novo ceramide biosynthesis affects aging phenotype in an in vitro model of neuronal senescence

This study shows that inhibiting de novo ceramide biosynthesis with L-cycloserine improves aging-related phenotypes in cultured cortical neurons.

Exenatide reverts the high-fat-diet-induced impairment of BDNF signaling and inflammatory response in an animal model of Alzheimer’s disease

This study shows exenatide improves BDNF signaling and reduces neuroinflammation in 3xTg-AD mice on a high-fat diet.