Author

Nicholas K. Haghani

University of California, DavisORCID 0000-0002-0489-9776Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Cole IngamellsiD· 2 shared Daniela C. SotoiD· 2 shared Gulhan KayaiD· 2 shared José M. Uribe‐SalazariD· 2 shared Keiko HinoiD· 2 shared Megan Y. DennisiD· 2 shared Sergi SimóiD· 2 shared Aarthi Sekar· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Cole IngamellsORCID

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3 papers

Recent·Most cited

Genome-wide in vivo dynamics of cohesin-mediated loop extrusion and its role in transcription activation

Tessa M. Popay, Ami Pant, Femke W. Munting, Melodi Tastemel, Morgan E Black, Nicholas K. Haghani, Jesse R. Dixon

This study investigates cohesin-mediated loop extrusion dynamics and its role in transcription activation by depleting NIPBL in vivo.

Nature Genetics · Feb 16, 2026Peer-reviewedMolecular Biology

Human-specific gene expansions contribute to brain evolution

Daniela C. Soto, José M. Uribe‐Salazar, Gulhan Kaya, Ricardo Valdarrago, Aarthi Sekar, Nicholas K. Haghani, Keiko Hino, Gabriana N. La, Natasha Ann F. Mariano, Cole Ingamells, Aidan E. Baraban, Zoeb N. Jamal, Tychele N. Turner, Eric D. Green, Sergi Simó, , Megan Y. Dennis

The paper identifies human-specific gene expansions linked to brain evolution by analyzing genome sequences and functional models in zebrafish.

Cell · Sep 1, 2025Peer-reviewedGenomics

Zebrafish models of human-duplicated SRGAP2 reveal novel functions in microglia and visual system development

José M. Uribe‐Salazar, Gulhan Kaya, KaeChandra Weyenberg, Brittany Radke, Keiko Hino, Daniela C. Soto, Jia-Lin Shiu, Wenzhu Zhang, Cole Ingamells, Nicholas K. Haghani, Emily Xu, Joseph Rosas, Sergi Simó, Joel B. Miesfeld, Tom M. Glaser, , Megan Y. Dennis

This paper uses zebrafish to study SRGAP2 duplication, showing its role in microglia and visual system development, with phenotypes resembling human conditions.

bioRxiv · Sep 11, 2024 · PreprintGenomics