Joel B. Miesfeld

This study identifies Foxp1 as a transcriptional regulator that coordinates early progenitor identity with neurogenic progression in the developing retina by activating early-stage genes and proneural factors while repressing late temporal factors.

The paper uses lineage tracing in zebrafish to identify atoh7 positive and negative retinal ganglion cell populations, showing 79% of RGCs originate from atoh7+ progenitors.

This paper uses zebrafish to study SRGAP2 duplication, showing its role in microglia and visual system development, with phenotypes resembling human conditions.

This study shows Yap regulates glucose utilization and nucleotide synthesis to support organ growth in zebrafish, with conserved mechanisms in mammals.

The paper shows that dense tissue packing and cell geometry regulate differentiation rate in zebrafish neural tube progenitors through Notch-dependent mechanisms.