José M. Uribe‐Salazar

Human-specific gene expansions contribute to brain evolution

The paper identifies human-specific gene expansions linked to brain evolution by analyzing genome sequences and functional models in zebrafish.

A conditional generative model to disentangle morphological variation from batch effects in model organism imaging studies

This paper introduces a conditional latent diffusion model to separate batch effects from morphological features in zebrafish imaging data, enabling accurate genotype classification.

Zebrafish models of human-duplicated SRGAP2 reveal novel functions in microglia and visual system development

This paper uses zebrafish to study SRGAP2 duplication, showing its role in microglia and visual system development, with phenotypes resembling human conditions.

Evaluation of CRISPR gene-editing tools in zebrafish

The paper evaluates CRISPR gene-editing tools in zebrafish by comparing in vivo editing efficiencies with computational predictions and analyzing control embryos for spurious effects.

Assessment of autism zebrafish mutant models using a high-throughput larval phenotyping platform

The paper develops a high-throughput phenotyping protocol for zebrafish larvae to assess autism-related mutant models, identifying morphological and behavioral defects in syngap1b and slc7a5 mutants.