Florian A Steiner

The paper identifies an SLBP-independent mechanism for maintaining maternal histone mRNA stability in C. elegans oogenesis, mediated by the PETISCO complex and TOST-1.

The paper shows that altered H3K27me3 landscapes can be inherited across generations in C. elegans, regulated by chromodomain proteins with opposing roles.

The paper shows that the N-terminal tail of CENP-A is required for de novo centromere establishment in C. elegans germ line but not for maintenance during embryogenesis.

This study shows that loss of histone H3.3 in C. elegans embryos causes replication defects, altered origin dynamics, and increased lethality under stress.

This study shows that H3.3K27M mutation causes DNA replication defects via JNK pathway misregulation in C. elegans, with implications for human tumor treatment.