Katrina McGuigan

Genomic repeatability and predictability of climate (mal)adaptation in a reef-building coral

Thermal adaptation in coral Stylophora pistillata is polygenic and largely population-specific across the Great Barrier Reef, yet range-wide models predict regional genotype-environment patterns and future maladaptation.

Background check: Mutational input to size variation depends on ancestor's breeding value

The paper examines how mutation contributions to size variation differ among genotypes with varying breeding values in Drosophila serrata, finding genotype-specific mutational biases and variances.

Heatwave winners and losers: cryptic coral holobionts differ in thermal tolerance

The paper examines thermal tolerance differences among cryptic coral taxa during a heatwave, finding that survival correlates with biological factors rather than environmental exposure.

Identification of multivariate phenotypes most influenced by mutation: Drosophila serrata wings as a case study

The paper identifies multivariate phenotypes most influenced by mutation using Drosophila serrata wing data, showing robust mutational variance across samples.

Genomic animal models quantify the heritable components of spatiotemporally structured phenotypic variation in a dispersive cryptobenthic marine fish

This study uses genomic animal models to analyze head shape variation in a marine fish, finding that phenotypic differentiation exceeds genetic differentiation at macrogeographic scales.

Effects of spontaneous mutations on survival and reproduction of Drosophila serrata infected with Drosophila C virus

This study examines how spontaneous mutations affect survival and reproduction in Drosophila serrata infected with Drosophila C virus, finding no directional bias in mutational effects on survival but pleiotropic effects on reproductive output.

Maintenance of quantitative genetic variance in complex, multi-trait phenotypes: The contribution of rare, large effect variants in two Drosophila species

The paper uses Bayesian Sparse Factor Genetic modelling to analyze gene expression traits in two Drosophila species, finding that most heritable trait covariation is due to a few extreme genotypes, suggesting the House of Cards model applies to co-expression phenotypes.

Causes of variability in estimates of mutational variance from mutation accumulation experiments

This study investigates variability in mutational variance estimates from mutation accumulation experiments, finding that sampling error and environmental factors contribute significantly to differences among estimates.