NeuroscienceNeuronPeer-reviewed
A photoswitchable GPCR-based opsin for presynaptic silencing
Bryan A. Copits, Raaj Gowrishankar, Patrick O’Neill…·Michael R. Bruchas
This paper introduces parapinopsin (PPO), a photoswitchable GPCR-based opsin that enables rapid and reversible presynaptic inhibition, and demonstrates its utility in vivo.
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