Chao Sun

The paper introduces Synapse Gigamapper, a protein language model that identifies synaptic localization motifs and reveals SERCA's role in excitatory synapses.

The paper investigates how mitochondria near synapses remodel to increase ATP production and support synaptic plasticity through structural and functional changes.

The paper identifies a proteasomal 19S subcomplex that regulates neuronal synapses independently of the 20S catalytic subunit through deubiquitylation of Lys63-ubiquitin.

This paper introduces an unbiased clustering algorithm for single-molecule localization microscopy that reduces false positives and negatives compared to existing methods.

The paper quantifies the spatial scale of synaptic protein allocation during homeostatic plasticity and finds that proteins are distributed at the level of synaptic neighborhoods.