Michele Sorelli

Myelinated fiber labeling and orientation mapping of the human brain with light-sheet fluorescence microscopy

The paper develops a method to label and map myelinated fibers in human brain tissue using light-sheet fluorescence microscopy and automated image analysis, enabling high-resolution structural characterization.

Quantitative cytoarchitectural phenotyping of deparaffinized human brain tissues

This paper develops a 3D imaging pipeline for automated quantitative cellular phenotyping of FFPE human brain tissues, revealing cytoarchitectural features in patients with cortical development malformations.

Anisotropic light propagation in human brain white matter

This study characterizes anisotropic light scattering in human white matter by measuring tensor components and correlating them with axon fiber orientation.

Two-photon all-optical electrophysiology for the dissection of larval zebrafish brain functional connectivity

The paper develops a two-photon optical system for high-speed volumetric recording and optogenetic stimulation in larval zebrafish to reconstruct functional connectivity of the left habenula.

MAGIC: A label-free fluorescence method for 3D high-resolution reconstruction of myelinated fibers in large volumes

The paper introduces MAGIC, a label-free fluorescence method for 3D high-resolution reconstruction of myelinated fibers in large volumes, demonstrating its application on multiple species brain samples.