Giacomo Mazzamuto

The paper develops a method to label and map myelinated fibers in human brain tissue using light-sheet fluorescence microscopy and automated image analysis, enabling high-resolution structural characterization.

This paper develops a 3D imaging pipeline for automated quantitative cellular phenotyping of FFPE human brain tissues, revealing cytoarchitectural features in patients with cortical development malformations.

The paper develops an all-optical system to inhibit cortical neurons and monitor responses, showing widespread suppression of sensory responses after optogenetic silencing.

This study shows that anesthesia levels affect the spatiotemporal features and functional connectivity of sensory-evoked responses in the mouse cortex, with the late component persisting under anesthesia.

This paper introduces a semi-supervised segmentation model for identifying supragranular and infragranular layers in human cerebral cortex MRI scans with high precision.

The paper develops BRANT, a tool for whole-brain neuronal activation mapping in mice, revealing strong sexual dimorphism in fear memory circuits.

This paper develops a method to 3D molecularly characterize cleared human brain tissues using light-sheet fluorescence microscopy.

The paper develops an imaging pipeline to create a cell census of the human cerebral cortex using MRI, immunohistochemistry, and light-sheet fluorescence microscopy.

This paper introduces a pipeline for 3D analysis of human brain cytoarchitecture at micrometer resolution, enabling quantitative evaluation of neuronal density and volume across different brain regions and subjects.

The paper introduces MAGIC, a label-free fluorescence method for 3D high-resolution reconstruction of myelinated fibers in large volumes, demonstrating its application on multiple species brain samples.