Non-histone human chromatin protein, PC4 is critical for genomic integrity and negatively regulates autophagy
Sweta Sikder, Sujata Kumari, Pallabi Mustafi, Nisha M. Ramdas, Swatishree Padhi, Arka Saha, Utsa Bhaduri, Birendranath Banerjee, Ravi R. Manjithaya, Tapas Kumar Kundu
This study shows that PC4 maintains genomic integrity by regulating chromatin structure and autophagy, with its loss increasing radiation resistance through autophagy enhancement.
FEBS Journal · Jun 6, 2019Peer-reviewedMolecular Biology