Author

Hassane El Mkami

University of St AndrewsORCID 0000-0002-0552-5784Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Assay:ChIP-seq· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Amanda L. HughesiD· 2 shared D. NormaniD· 2 shared Ramasubramanian SundaramoorthyiD· 2 shared Tom Owen‐HughesiD· 2 shared Barbara TreutleiniD· 1 shared Bettina BöttcheriD· 1 shared Daniel RyaniD· 1 shared Dmitri I. SverguniD· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMolecular Biology

Amanda L. HughesORCID

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2 papers

Recent·Most cited

Molecular BiologyeLifePeer-reviewedFeb 25, 2018

Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome

Ramasubramanian Sundaramoorthy, Amanda L. Hughes, Hassane El Mkami…·Tom Owen‐Hughes

The paper presents structures of yeast Chd1 bound to a ubiquitinylated nucleosome, revealing how it interacts with DNA and histone modifications.

103 citationstop 2%

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Molecular BiologyeLifePeer-reviewedMar 23, 2017

Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes.

Ramasubramanian Sundaramoorthy, Amanda L. Hughes, Vijender Singh…·Tom Owen‐Hughes

This study models the structural changes in the Chd1 protein when bound to nucleosomes, revealing how ATP binding alters its conformation and DNA interactions.

62 citationstop 4%

yeastexperimental assay

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