BiophysicsbioRxivPreprint
CD95/Fas Apoptosis Signal Initiation Depends on the Ligand Oligomerization State and Formation of Small Ligand-Receptor Complexes
Xiaoyue Shang, Nina Bartels, Nicolaas T M van der Voort…·Cornelia Monzel
This study investigates how CD95 ligand oligomerization and receptor-ligand stoichiometry influence apoptotic signaling, showing that trimeric ligands and bridging enhance receptor engagement and signaling potency.
DOI 10.64898/2026.05.07.723507