Author

Nina Bartels

Heinrich Heine University DüsseldorfORCID 0009-0004-5199-9106Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Cornelia MonzeliD· 2 shared Gajen Thaventhiran· 2 shared Xiaoyue ShangiD· 2 shared Amelie Heuer‐JungemanniD· 1 shared Andreas NeuschiD· 1 shared Claus A. M. SeideliD· 1 shared J. BasquiniD· 1 shared Johann Moritz WeckiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

Cornelia MonzelORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintMay 8, 2026

CD95/Fas Apoptosis Signal Initiation Depends on the Ligand Oligomerization State and Formation of Small Ligand-Receptor Complexes

Xiaoyue Shang, Nina Bartels, Nicolaas T M van der Voort…·Cornelia Monzel

This study investigates how CD95 ligand oligomerization and receptor-ligand stoichiometry influence apoptotic signaling, showing that trimeric ligands and bridging enhance receptor engagement and signaling potency.

DOI 10.64898/2026.05.07.723507

humanproteomics

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Cell BiologyBMC BiotechnologyPeer-reviewedJul 1, 2025

High yield purification of an Isoleucine zipper modified CD95 Ligand with either biotin or DNA-oligomer binding domain for efficient Cell Apoptosis Induction

Xiaoyue Shang, Nina Bartels, Johann Moritz Weck…·Cornelia Monzel

This paper describes the design and production of a stabilized CD95L variant with improved apoptosis induction efficiency and functionalization capabilities.

2 citations

humanprotein structure

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