Author

Gajen Thaventhiran

Heinrich Heine University Düsseldorf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Cornelia MonzeliD· 2 shared Nina BartelsiD· 2 shared Xiaoyue ShangiD· 2 shared Amelie Heuer‐JungemanniD· 1 shared Andreas NeuschiD· 1 shared Claus A. M. SeideliD· 1 shared J. BasquiniD· 1 shared Johann Moritz WeckiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

Cornelia MonzelORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

CD95/Fas Apoptosis Signal Initiation Depends on the Ligand Oligomerization State and Formation of Small Ligand-Receptor Complexes

Xiaoyue Shang, Nina Bartels, Nicolaas T M van der Voort, Andreas Neusch, Noah Salama, Gajen Thaventhiran, Ralf Kühnemuth, Suren Felekyan, Claus A. M. Seidel, Cornelia Monzel

This study investigates how CD95 ligand oligomerization and receptor-ligand stoichiometry influence apoptotic signaling, showing that trimeric ligands and bridging enhance receptor engagement and signaling potency.

bioRxiv · May 8, 2026 · PreprintBiophysics

High yield purification of an Isoleucine zipper modified CD95 Ligand with either biotin or DNA-oligomer binding domain for efficient Cell Apoptosis Induction

Xiaoyue Shang, Nina Bartels, Johann Moritz Weck, Sabine Suppmann, J. Basquin, Gajen Thaventhiran, Amelie Heuer‐Jungemann, Cornelia Monzel

This paper describes the design and production of a stabilized CD95L variant with improved apoptosis induction efficiency and functionalization capabilities.

BMC Biotechnology · Jul 1, 2025Peer-reviewedCell Biology