Xiaoyue Shang

This study investigates how CD95 ligand oligomerization and receptor-ligand stoichiometry influence apoptotic signaling, showing that trimeric ligands and bridging enhance receptor engagement and signaling potency.

This paper describes the design and production of a stabilized CD95L variant with improved apoptosis induction efficiency and functionalization capabilities.

This study evaluates DNA origami-based nanoagents' ability to induce apoptosis in 3D spheroids, finding that rigid FasL attachment strategies are more effective than flexible ones.