Ewa Bielczyk-Maczyńska

This study identifies novel causal genes for NAFLD using a combination of GWAS, genetic colocalization, and CRISPRi functional screens.

CROP-Seq uses CRISPRi and scRNA-Seq to screen gene targets in adipocytes, identifying gene knock-down effects and novel regulators of adipogenesis and metabolic disease.

This paper establishes a zebrafish rad51 loss-of-function model that recapitulates Fanconi anemia symptoms, showing hematopoietic defects and tumor predisposition upon p53 co-mutation.