Annapaola Andolfo

This study shows that GCase deficiency in microglia leads to metabolic changes and ATP depletion, impairing their neuroprotective functions and increasing neuronal vulnerability in Parkinson's disease.

This study develops a glia-enriched 3D brain model from human iPSCs that mimics MS-related neurodegenerative phenotypes and intercellular communication.

MargheRita streamlines MS-DIAL output analysis and metabolite identification in R by providing a comprehensive pipeline for LC-MS/MS data, enhancing fragment matching accuracy with a curated spectral library.