Cancer BiologybioRxivPreprint
Midkine Drives Reawakening of Dormant Melanoma Metastases
Carolina Rodríguez-Tirado, Thoufiqul Alam Riaz, Alcina A. Rodrigues…·María Soledad Sosa
This paper identifies Midkine as a factor that disrupts melanoma dormancy by suppressing NR2F1 and altering signaling pathways, showing that targeting both Midkine and NR2F1 can limit metastasis and extend survival in mouse models.
2 citations