Pharmacology & ToxicologybioRxivPreprint
Suppressing Bone Resorption and Promoting Mineralization with Tetracycline Derivatives
Saeka Shimochi, Katja Hrovat, Uruj Sarwer…·Miho Nakamura
This study evaluates the effects of tetracycline derivatives on bone cells, finding dose-dependent dual effects on osteoclasts and osteoblasts, suggesting potential as dual-function therapies for osteoporosis.