Author

Leire Bergara-Muguruza

University of TurkuORCID 0000-0003-1526-452XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Ari Alho· 2 shared Katja Hrovat· 2 shared Keijo T MäkeläiD· 2 shared Maarit LaineiD· 2 shared Miho NakamuraiD· 2 shared Ainara Castellanos–RubioiD· 1 shared Aïsha CallebautiD· 1 shared Akihisa OtakaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPharmacology & Toxicology

Ari Alho

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3 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintFeb 25, 2026

Suppressing Bone Resorption and Promoting Mineralization with Tetracycline Derivatives

Saeka Shimochi, Katja Hrovat, Uruj Sarwer…·Miho Nakamura

This study evaluates the effects of tetracycline derivatives on bone cells, finding dose-dependent dual effects on osteoclasts and osteoblasts, suggesting potential as dual-function therapies for osteoporosis.

DOI 10.64898/2026.02.24.707630

humanzebrafish

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BioengineeringbioRxivPreprintFeb 18, 2026

Electrical Surface Polarization as a Functionalization Strategy to Improve Bone Regeneration of Apatite-Based Graft Materials

Katja Hrovat, Leire Bergara-Muguruza, Rumi Hiratai…·Miho Nakamura

This study shows electrical surface polarization improves bone regeneration of apatite-based grafts by enhancing osteoclast activity and implant-bone integration in vivo.

DOI 10.64898/2026.02.17.705299

ratexperimental assay

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ImmunologybioRxivPreprintDec 2, 2025

Long non-coding RNAs as a novel source of beta cell autoantigens in type 1 diabetes

Jon Mentxaka, Aïsha Callebaut, Koldo García‐Etxebarria…·Izortze Santín

This study identifies lncRNA-derived peptides that act as autoantigens in type 1 diabetes by activating CD4+ T cells through HLA-II restricted epitopes.

DOI 10.64898/2025.12.01.691527

humanproteomics

𝕏 PostBluesky