High-throughput protein binder discovery by rapid in vivo selection
Matthew J. Styles, Joshua A. Pixley, Tongyao Wei, Christopher Basile, Shannon S. Lu, Bryan C. Dickinson
This paper introduces PANCS-binders, an in vivo selection method for discovering protein binders, and demonstrates its ability to screen billions of variants against multiple targets in two days.
bioRxiv · Jan 6, 2025 · PreprintSynthetic Biology