Monique M.B. Breteler

This study identifies genetic variants associated with missing metabolite measurements in two population-based cohorts, suggesting missingness is partly genetic and relevant for clinical and epidemiological research.

The paper develops an in vitro platform to screen immune senomodulators using human-derived immune cells, enabling personalized anti-aging treatments through multi-scale molecular analysis.

The paper introduces searchSTR, a tool for genome-wide STR somatic instability analysis, and finds associations between STR instability and age, sex, brain morphology, and neurodegeneration markers.

This paper identifies a novel genetic locus associated with olfactory dysfunction through a genome-wide association study meta-analysis and shows causal links to various health outcomes.

This study conducts a GWAS of human pineal gland volume, identifying 34 genome-wide significant loci and highlighting genes and pathways related to sleep, metabolism, and neurodegeneration.

This study identifies 54 genome-wide significant loci for enlarged perivascular spaces using GWAS across two cohorts, highlighting vascular and inflammatory pathways.

This study identifies 48 genetic variants associated with handedness using a large GWAS, highlighting polygenic nature and genetic links to neuropsychiatric traits.