Author

Silvia T. Cardona

University of ManitobaORCID 0000-0002-0629-8886Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

A. S. M. Zisanur RahmaniD· 1 shared Andrew M. HoganiD· 1 shared Anna MotnenkoiD· 1 shared Archit DevarajaniD· 1 shared Darío Fernández Do PortoiD· 1 shared David Bernard LeviniD· 1 shared Egor A. SyroeginiD· 1 shared Ernesto Quintana· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. S. M. Zisanur RahmanORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Burkholderia vietnamiensis Genes Involved in Extracellular Medium-Chain-Length Polyhydroxyalkanoate Degradation

Zhong Ling Yap, Sion Yi, Ernesto Quintana, Gabriel G. Lucas, Mohamad Safklou, Ryan Darragh, Andrew M. Hogan, Anna Motnenko, Warren A. Blunt, Richard Sparling, Darío Fernández Do Porto, David Bernard Levin, Silvia T. Cardona

This paper identifies genes in Burkholderia vietnamiensis responsible for extracellular degradation of medium-chain-length polyhydroxyalkanoates using transposon mutagenesis, Tn-seq, and CAST.

Applied and Environmental Microbiology · Apr 3, 2026Peer-reviewedMicrobiology

Rationally Designed Pooled CRISPRi-seq Uncovers an Inhibitor of Bacterial Peptidyl-tRNA Hydrolase

A. S. M. Zisanur Rahman, Egor A. Syroegin, Julieta Novomisky Nechcoff, Archit Devarajan, Yury S. Polikanov, Silvia T. Cardona

The paper introduces CIMPLE, a rationally designed CRISPRi pooled library, to uncover antibiotic targets by improving genomic coverage of essential genes during drug exposure.

Cell Reports · Nov 1, 2024Peer-reviewedMicrobiology