MicrobiologyCell ReportsPeer-reviewed
Rationally Designed Pooled CRISPRi-seq Uncovers an Inhibitor of Bacterial Peptidyl-tRNA Hydrolase
A. S. M. Zisanur Rahman, Egor A. Syroegin, Julieta Novomisky Nechcoff…·Silvia T. Cardona
The paper introduces CIMPLE, a rationally designed CRISPRi pooled library, to uncover antibiotic targets by improving genomic coverage of essential genes during drug exposure.
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