Turncoat antibodies unmasked in a model of autoimmune demyelination: from biology to therapy
Reza Taghipour-Mirakmahaleh, Françoise Morin, Yu Zhang, Louis Bourhoven, Louis‐Charles Béland, Qun Zhou, Julie A. Jaworski, Anna Park, Juan Manuel Dominguez, Jacques Corbeil, Eoin P. Flanagan, Romain Marignier, Catherine Larochelle, Steven M. Kerfoot, Luc Vallières
This study identifies pathogenic autoantibodies in EAE and demonstrates a therapeutic approach using a synthetic antibody to block their activity.
Proceedings of the National Academy of Sciences · Dec 17, 2025Peer-reviewedImmunology