Author
Centre Hospitalier de l’Université de MontréalORCID 0000-0002-8724-4782Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Jake S. Rhodes, Adrien Aumon, Sacha Morin…·Kevin R. Moon
The paper introduces RF-PHATE, a supervised data visualization method that integrates expert knowledge to enhance interpretation of complex biological data.
Haley E. Randolph, Raúl Aguirre‐Gamboa, Elsa Brunet‐Ratnasingham…·Luis Bruno Barreiro
This study identifies gene-environment interactions influencing immune response to SARS-CoV-2 in hospitalized patients using single-cell RNA-sequencing and eQTL analysis.
Reza Taghipour-Mirakmahaleh, Françoise Morin, Yu Zhang…·Luc Vallières
This study identifies pathogenic autoantibodies in EAE and demonstrates a therapeutic approach using a synthetic antibody to block their activity.
Sonia T. Gazeau, Xiaoyan Deng, Elsa Brunet‐Ratnasingham…·Morgan Craig
This study uses virtual patient cohorts to model immune response differences in cancer and immunosuppressed COVID-19 patients, identifying key immune dysregulation factors.
Guillaume Bernas, Mariette Ouellet, Andréa Barrios…·Jean-François Schmouth
The paper describes a modified electroporation method to generate conditional allele mouse models using two strategies, achieving targeting efficiencies between 3-25% for eight genes.
Channabasavaiah B. Gurumurthy, Aidan R. O’Brien, Rolen M. Quadros…·Atsushi Yoshiki
The paper re-evaluates the efficiency of a CRISPR-Cas9 method for generating conditional knockout alleles in mice, finding very low success rates and high rates of undesired alleles.