Author

Sarah Cherkaoui

University of ZurichORCID 0000-0002-0636-4177Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:metabolomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alaa OthmaniD· 1 shared Allison E. Ashley‐KochiD· 1 shared Beata VekeriotaiteiD· 1 shared Berend SnijderiD· 1 shared Cantin BaroniD· 1 shared Christine Des RosiersiD· 1 shared Claus BendtseniD· 1 shared D. Sean FroeseiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperSystems Biology

Alaa OthmanORCID

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3 papers

Recent·Most cited

NeuroscienceCommunications BiologyPeer-reviewedMar 11, 2025

Mitochondrial dysfunction drives a neuronal exhaustion phenotype in methylmalonic aciduria

Matthew C.S. Denley, Monique S. Straub, Giulio Marcionelli…·Matthias R. Baumgartner

This study uses patient-derived neurons to show mitochondrial dysfunction in MMA leads to neuronal exhaustion and altered excitability.

11 citationstop 2%

humanbulk RNA-seq

Systems BiologyiSciencePeer-reviewedNov 14, 2023

Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results

Cantin Baron, Sarah Cherkaoui, Sandra Therrien-Laperriere…·Julie Hussin

This paper introduces the shortest reactional distance (SRD) metric to improve the biological interpretation of metabolite genome-wide association study (mGWAS) results by linking genes to metabolites based on metabolic pathway knowledge.

4 citations

humanmetabolomics

Systems BiologyMolecular Systems BiologyPeer-reviewedNov 1, 2022

Epithelial-mesenchymal transition is the main driver of intrinsic metabolism in cancer cell lines

Sarah Cherkaoui, Stephan Durot, Jenna Bradley…·Nicola Zamboni

The paper profiles the metabolome of 180 cancer cell lines and identifies two major metabolic types linked to epithelial-mesenchymal transition (EMT).

33 citations

humanmetabolomics