Christine Des Rosiers

This study shows that dietary protein sources affect hepatic steatosis and insulin resistance on obesogenic diets through carnitine-dependent regulation of ACC2.

This paper identifies 4,5-dihydroxyhexanoic acid as a biomarker for mitochondrial disease severity and links it to GABA metabolism.

This study investigates whether inhibiting stearoyl-CoA desaturase (SCD) restores sleep in 3xTg-AD mice and affects astrocytic function, finding no significant restoration of sleep patterns but partial rescue of astrocytic changes in the hippocampus.

This study uses machine learning and explainable AI to identify metabolite markers for heart failure, finding that lignoceric acid is a significant discriminator.

This paper introduces the shortest reactional distance (SRD) metric to improve the biological interpretation of metabolite genome-wide association study (mGWAS) results by linking genes to metabolites based on metabolic pathway knowledge.

The paper functionally screens IBD genes in intestinal epithelial cells to identify their roles in epithelial structure and function, revealing DUSP16's role in mucosal defense.