Author

Naomi Yamamoto

University of WashingtonORCID 0000-0002-0641-6547Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Adrianne Wallace-PovirkiD· 1 shared Aidan SchutteriD· 1 shared Alexander E. Orellana· 1 shared Camilla Rydberg MillrudiD· 1 shared Débora Barbosa Vendramini Costa· 1 shared Faiyaz NottaiD· 1 shared Gregory Lawrence BeattyiD· 1 shared Gun Ho JangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Adrianne Wallace-PovirkORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

HMGA2 Expression in Pancreatic Ductal Adenocarcinoma Controls Tumor Microenvironment and Immunosuppression via IL1α

Naomi Yamamoto, Stephanie Dobersch, Tess M. Robertson, Jae Hyung Sim, Adrianne Wallace-Povirk, Nayvin W. Chew, Alexander E. Orellana, Joana E. Aggrey-Fynn, Liberalis Debraj Boila, Aidan Schutter, Ian M. Loveless, Gun Ho Jang, Shayan Avanessian, Gregory Lawrence Beatty, Suni R Hingorani, , Sita Kugel

This study shows HMGA2 in PDAC drives immunosuppressive TME by upregulating IL1α, which promotes CAFs and reduces CD8+ T cells, and blocking IL1 improves tumor control with KRAS inhibitors.

bioRxiv · Oct 6, 2026 · PreprintCancer Biology