Author

Stefan Oliver Bassler

European Molecular Biology LaboratoryORCID 0000-0002-0652-9242Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Athanasios TypasiD· 2 shared Adam J. MulkerniD· 1 shared Kiran Raosaheb PatiliD· 1 shared Natalia GabrielliiD· 1 shared R. Craig MacLeaniD· 1 shared Sergej AndrejeviD· 1 shared Vinita PeriwaliD· 1 shared William MatlockiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

Athanasios TypasORCID

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2 papers

Recent·Most cited

DNA-damaging combination treatments impose genotype-specific constraints on hypermutator evolvability

Adam J. Mulkern, Stefan Oliver Bassler, William Matlock, Athanasios Typas, R. Craig MacLean

This study shows that combining DNA-damaging agents with antibiotics can reduce resistance evolution in specific hypermutator bacterial genotypes but not others.

bioRxiv · Feb 20, 2026 · PreprintMicrobiology

Bioactivity assessment of natural compounds using machine learning models based on drug target similarity

Vinita Periwal, Stefan Oliver Bassler, Sergej Andrejev, Natalia Gabrielli, Kiran Raosaheb Patil, Athanasios Typas

This paper develops a machine learning model to predict protein targets of natural compounds based on drug target similarity, identifying potential therapeutics with experimental validation.

bioRxiv · Nov 6, 2020 · PreprintBioinformatics