Selective YAP activation in Procr cells is essential for ovarian stem/progenitor expansion and epithelium repair
Jingqiang Wang, Chunye Liu, Lingli He, Zhiyao Xie, Lanyue Bai, Wentao Yu, Zuoyun Wang, Yi Lu, Dong Gao, Junfen Fu, Lei Zhang, Yi Arial Zeng
The paper shows that YAP activation in Procr+ ovarian progenitors is essential for OSE repair and stem/progenitor expansion through reduced Vgll4 expression and increased Procr transcription.
eLife · Feb 25, 2022Peer-reviewedDevelopmental Biology