Cell Painting in activated cells illuminates phenotypic dark space and uncovers novel drug mechanisms of action.
Matylda Zietek, Akshar Lohith, Derfel Terciano, Beverley M. Rabbitts, Aswad Khadilkar, John B. MacMillan, R. Scott Lokey
The paper uses Cell Painting to identify phenotypic effects of compounds in activated cells, revealing novel drug mechanisms and expanding phenotypic understanding.
bioRxiv · May 23, 2025 · PreprintSystems Biology