Fast structural search for classification of gut bacterial mucin O-glycan degrading enzymes
Mert Erden, Tyler J. Schult, Karin Yanagi, Jugal Kishore Sahoo, David Lee Kaplan, Lenore Cowen, Kyongbum Lee
This paper introduces DEFT, a method that combines sequence- and structure-based approaches to improve EC number prediction accuracy and enable high-throughput enzyme repertoire annotation.
PLoS Computational Biology · Sep 25, 2026Peer-reviewedBioinformatics