Systems genetics analyses in Diversity Outbred mice inform human bone mineral density GWAS and identify Qsox1 as a novel determinant of bone strength
Basel Maher Al-Barghouthi, Larry D. Mesner, Gina M. Calabrese, Daniel J. Brooks, Steven M. Tommasini, Mary Bouxsein, Mark C. Horowitz, Clifford james Rosen, Kevin K. Nguyen, Samuel Haddox, Emily Farber, Suna Önengüt-Gümüşcü, Daniel Pomp, Charles R. Farber
The paper uses Diversity Outbred mice to analyze bone traits and identify novel genes associated with bone strength, informing human GWAS findings.
Nature Communications · Jun 7, 2021Peer-reviewedGenetics