Author

Christopher Leonard Brett

Concordia UniversityORCID 0000-0002-0730-3405Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Christopher Leonard Brett1 paper

Biology Disciplines

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Synthetic Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

Joseph Trani· 2 shared Aashiq Hussain KachrooiD· 1 shared Alexander Christophe Pawelczak· 1 shared Dipti Patel· 1 shared Jeff BouffardiD· 1 shared Marie LaufensiD· 1 shared Mόnica Núñez-Soto· 1 shared Sara Daneshi· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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2 shared papersSynthetic Biology

Joseph Trani

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3 papers

Recent·Most cited

Human ORFeome expression in S. cerevisiae to better understand extracellular vesicle biology

Joseph Trani, Sara Daneshi, Aashiq Hussain Kachroo, Christopher Leonard Brett

The paper uses human ORFeome expression in yeast to study conserved mechanisms of extracellular vesicle cargo sorting.

bioRxiv · Sep 9, 2026 · PreprintSynthetic Biology

Engineering S. cerevisiae extracellular vesicles using synthetic biology

Jeff Bouffard, Joseph Trani, Alexander Christophe Pawelczak, Marie Laufens, Mόnica Núñez-Soto, Christopher Leonard Brett

This paper engineers S. cerevisiae extracellular vesicles using synthetic biology to identify effective scaffold proteins for cargo loading and human protein sorting.

bioRxiv · Mar 6, 2026 · PreprintSynthetic Biology

Acetate and hypertonic stress stimulate organelle membrane fission using distinct phosphatidylinositol signals

Dipti Patel, Christopher Leonard Brett

The paper describes a fluorometric assay to study vacuole fission in yeast and shows acetate and hypertonic stress trigger fission via distinct phosphatidylinositol signaling pathways.

bioRxiv · Aug 23, 2018 · PreprintCell Biology