Emma Danhash

This study shows that C4 deficiency reduces amyloid plaques and neuroinflammation in a mouse AD model, suggesting C4's role in glial reactivity and pathology.

This study shows that loss of Ms4a4a remodels microglial transcriptional programs and reduces dense-core plaque-associated tau spreading in a mouse model of Alzheimer's disease.

This study shows that Ms4a4a deficiency reduces amyloid beta pathology in mice by enhancing Aβ clearance, supported by increased MMP-9 production in microglia and human CSF data.