Collin J. Nadarajah

This study shows that C4 deficiency reduces amyloid plaques and neuroinflammation in a mouse AD model, suggesting C4's role in glial reactivity and pathology.

This study shows that Ms4a4a deficiency reduces amyloid beta pathology in mice by enhancing Aβ clearance, supported by increased MMP-9 production in microglia and human CSF data.

This study shows that microglia drive diurnal variation in BBB permeability during inflammation, with increased BBB breakdown following evening LPS injection.

This study shows BMAL1 regulates astrocyte activation and function through cell-autonomous and non-cell-autonomous mechanisms, impacting neuronal survival and brain health.