Author

Jacob Aaron Klickstein

Massachusetts General HospitalORCID 0000-0002-0759-4724Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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2019-2024 · peak 1/yr

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Chloe K. NobuharaORCID

Mutual co-authors in cluster

2 papers

NeuroscienceStem Cell ReportsPeer-reviewedFeb 8, 2024

This study shows that the p97 R155H mutation impairs lysophagy in motor neurons, leading to lysosomal dysfunction and reduced viability.

19 citationstop 4%

Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedApr 1, 2019

This study evaluates ELISA-based quantification of PrP in CSF as a biomarker for PrP-reducing therapeutics, showing its reliability and CNS origin.

51 citations