Author

Sı́lvia Beà

Hospital Clínic de BarcelonaORCID 0000-0001-7192-2385Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Elı́as CampoiD· 2 shared Renée BeekmaniD· 2 shared A. Marieke OudelaariD· 1 shared Agostina BianchiiD· 1 shared Alastair SmithiD· 1 shared Alfonso María ValenciaiD· 1 shared Andrea Rivero· 1 shared Angela Vicente-LuqueiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Elı́as CampoORCID

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3 papers

Recent·Most cited

Establishment and Characterization of a CCND1-Rearranged Non-Mantle Cell Lymphoma Cell Line and Patient-Derived Xenograft Model

Claus Moritz Graef, Moritz Reese, Angela Vicente-Luque, Nicolas Mönig, Charlotte Bruzeau, Ferran Nadeu, Maria Latacz, Johanna I. Bihler, Jörn Meinel, Maria Cartolano, Martin Peifer, Sílvia Beà, Elı́as Campo, Melanie Thelen, Paul Jan Bröckelmann, Ron Daniel Jachimowicz

The paper establishes and characterizes a patient-derived cell line and xenograft model for a CCND1-rearranged non-Mantle Cell Lymphoma, showing they recapitulate tumor biology and drug resistance.

Leukemia · Jan 26, 2026Peer-reviewedCancer Biology

Translocations can drive expression changes of multiple genes in regulons covering entire chromosome arms

Anna Oncins, Roser Zaurín, Houyem Toukabri, Kimberly Quililan, José R Hernández Mora, Magdalena A. Karpińska, Erik Wernersson, Alastair Smith, Agostina Bianchi, Leone Albinati, Luca Cozzuto, Andrea Rivero, Chloe Gulliver, Jessica Velten, Johanna Denkena, , Renée Beekman

This study shows translocations can drive widespread gene expression changes across entire chromosome arms in MCL by altering chromatin organization and regulatory loops.

Nucleic Acids Research · Aug 11, 2025Peer-reviewedCancer Biology

Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation

Roser Vilarrasa‐Blasi, Paula Soler-Vila, Núria Verdaguer-Dot, Núria Russiñol, Marco Di Stefano, Vicente Chapaprieta, Guillem Clot, Irene Farabella, Pol Cuscó, Marta Kulis, Xabier Agirre, Felipe Prósper, Renée Beekman, Sı́lvia Beà, Dolors Colomer, , José Ignacio Martín-Subero

This study examines 3D genome architecture changes during B cell differentiation and in B cell neoplasias using Hi-C and multi-omic data, revealing dynamic compartment shifts and tumor-specific chromatin reorganization.

Nature Communications · Jan 28, 2021Peer-reviewedGenomics