Pascal Schneider

This study compares the substrate scope of a modern and ancestral family-1 glycosidase, finding the ancestral enzyme more efficient with large aglycon-containing flavonoid glycosides.

The paper identifies BCMA signaling from the Golgi apparatus in DLBCL, showing APRIL-mediated activation of NF-κB and subsequent proteosomal degradation.

This paper develops an active soluble LIGHT protein that promotes immune cell infiltration and delays tumor growth in a melanoma model.

The paper models Edar expression dynamics to reveal hidden patterning processes in tooth signaling centers, showing a two-step activation and erasure mechanism.

This study shows that the Pax9/Wnt pathway regulates mouse palate formation, with Wnt agonist therapy correcting cleft palate defects in Pax9-deficient mice.