Juvenile protein restriction compresses sexual dimorphism in mice
Amélie Joly, Lucas Rebiffé, Anne Lambert, Estelle Caillon, Sandrine Hughes, Benjamin Gillet, Mickael Zergane, Isabelle Rahioui, Pedro Da Silva, Chantal Rigaud, Ingrid Plotton, Justine Bruse, Hervé Guillou, Anne Fougerat, François Leulier, Filipe De Vadder
This study shows that juvenile protein restriction in mice reduces sexual dimorphism by affecting somatic growth, energy metabolism, and hepatic molecular identity, with distinct adaptations in reproductive development.
bioRxiv · Jul 9, 2025 · PreprintPhysiology