Steven P. LaRosa

Increased mannosylation of extracellular vesicles in Long COVID plasma provides a potential therapeutic target for Galanthus nivalis agglutinin (GNA) affinity resin

The paper identifies increased mannosylation of extracellular vesicles in Long COVID plasma and shows GNA affinity resin can remove them, potentially rebalancing immune and tissue-repair networks.

Ex Vivo Removal of CD41 positive platelet microparticles from Plasma by a Medical Device containing a Galanthus nivalis agglutinin (GNA) affinity resin

This study demonstrates that the Hemopurifier device removes 98.5% of platelet microparticles from healthy human plasma in a 4-hour session.

The Hemopurifier removes extracellular vesicles and microRNAs from renal perfusates following controlled oxygenated rewarming of discarded donor kidneys

The paper demonstrates that the Hemopurifier reduces extracellular vesicles, dsDNA, and microRNAs in perfusates from discarded donor kidneys, suggesting potential benefits for kidney transplantation.