John Daniel Kelly

This study uses multiomic and spatial profiling of colorectal tissue and blood to show that Long COVID is linked to immune dysregulation and viral persistence, with stronger signals in tissue than blood.

The paper identifies increased mannosylation of extracellular vesicles in Long COVID plasma and shows GNA affinity resin can remove them, potentially rebalancing immune and tissue-repair networks.

This study examines how pre-existing neutralizing antibodies affect viral shedding in post-vaccination SARS-CoV-2 infections, finding that higher titers reduce viral load and duration but are less effective against Omicron variants.