An intrinsic endothelial dysfunction causes cerebral small vessel disease
Sophie Quick, Tessa V. Procter, Jonathan Moss, Angus Lawson, Serena Baker, Marc Walton, Mehreen Mohammad, Will Mungall, Ami Onishi, Zuzanna Tobola, Michael S. Stringer, Maurits A. Jansen, Antoine Vallatos, Ylenia Giarratano, Miguel O. Bernabéu, , Anna Williams
This study identifies intrinsic endothelial dysfunction as a cause of cerebral small vessel disease in a normotensive rat model, independent of hypertension.
bioRxiv · Dec 13, 2021 · PreprintNeuroscience